SLE-DAS

Neuropsychiatric features included in the SLICC classification criteria for SLE, including recent onset of seizure, psychosis, organic brain syndrome, acute confusional state, SLE retinal changes, peripheral neuropathy myelopathy, lupus headache, cerebrovascular accident and aseptic meningitis.

2. Systemic vasculitis

Systemic vasculitis involving large and medium-sized vessels or lupus enteritis.

3. Mucocutaneous vasculitis

Any mucocutaneous vasculitis or chilblain lupus.

4. Cardiac/Pulmonary involvement

Including shrinking lung, interstitial pneumonitis, diffuse alveolar hemorrhage, pulmonary hypertension, myocarditis, valvular dysfunction, Libman-Sacks endocarditis.

Pleurisy, pericarditis or sterile peritonitis.

6. Proteinuria

Ratio mg/g or mg/24 h

Urinary protein-creatinine ratio (mg/g) or 24h urinary protein (mg/24h), above 500mg/g and 500mg/24h, respectively.

7. Arthritis

28 swollen joint count

Number of swollen joints in 28 joint count.

Proximal muscle aching/weakness with elevated CPK/aldolase or electromyogram changes or a biopsy showing myositis.

9. Localized skin rash

Acute, subacute or chronic cutaneous lupus rashes included in the SLICC classification criteria, located only above the neck.

10. Generalized skin rash

Acute, subacute and chronic cutaneous lupus rashes included in the SLICC classification criteria, located below the neck (with or without rash above the neck).

Abnormal, patchy or diffuse loss of hair.

Oral or nasal ulcerations.

13. Hemolytic anemia

Anemia with positive direct Coombs test, increased serum LDH, and low serum haptoglobin.

14. Thrombocytopenia

Platelet count(G/L)

Platelet count (G/L), below 100 G/L platelets.

15. Leukopenia

Leukocyte count(G/L)

Leukocyte count (G/L), below 3 G/L white blood cells.

16. Hypocomplementemia

Decrease in C3 or C4 below the lower limit of normal for testing laboratory.

17. Increased anti-dsDNA

Increase in DNA binding above the upper limit of normal for testing laboratory.